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Dexamethasone 0.5mg 1mg 4mg 8mg – “decadron, Dectancyl, Dexamonozon, Dexona, Dexasone, Diodex, Fortecortin, Maxidex, Oradexon, Wymesone, DexPak, Dexone” “Allergy, Asthma, Atopic Dermatitis, Allergic Rhinitis”
Dexamethasone is a type of corticosteroid medication.
The long-term use of dexamethasone may result in thrush, bone loss, cataracts, easy bruising, or muscle weakness.
Dexamethasone was first made in 1957.
1 Medical use
1.1 Anti-inflammatory
1.2 Cancer
Combined lenalidomide and bortezomib maintenance was studied in patients with high-risk multiple myeloma. 38 In this study, patients received ASCT followed by up to 3 years of maintenance therapy with bortezomib, lenalidomide and dexamethasone maintenance followed by indefinite lenalidomide maintenance.

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  • The IGF-I binding to dexamethasone -treated cells (50 nM for 24 hr on the day prior to confluence) resulted in an increased number of available binding sites, with no effect on the binding affinities. FACS analysis showed in macrophages treated with CTLA4-Ig alone, CTLA4-Ig-DEX and CTLA4-Ig-DEX-MTX a CD86 decrease of almost 35%, versus untreated cells (CNT).Early dispersal of the primary tumor renders localized therapy ineffective.
  • J Child Adolesc Psychopharmacol. 2009 Aug;19(4):385-94. Even a single seizure negatively impacts pediatric health-related quality of life. Epilepsia. 2009 Sep;50(9):2110-6. Obesity is a common comorbidity for pediatric patients with untreated, newly diagnosed epilepsy. Neurology. 2009 Sep 1;73(9):658-64. Core elements of epilepsy diagnosis and management: expert consensus from the Leadership in Epilepsy, Advocacy, and Development (LEAD) faculty.The goal of this research is to personalize medicine using pharmacogenetics, to ensure that each patient receives an individualized dose of the optimal medication.There she studied pharmacogenomics, and identified genetic variants associated with clearance of the drug methotrexate. Antileukemic efficacy of continuous vs discontinuous dexamethasone in murine models of acute lymphoblastic leukemia. PLOS ONE. 2015 Aug 7;10(8):e0135134. Genome-wide analysis links NFATC2 with asparaginase hypersensitivity. Blood. 2015 Jul 2;126(1):69-75. Epigenetic up-regulation of the NLRP3 inflammasome in leukemia cells causes glucocorticoid resistance by CASP1 cleavage of the glucocorticoid receptor. Nat Genet. 2015 Jun;47(6):607-14. European Journal of Cancer. 2014 Oct;50(15):2685-94. Host thiopurine methyltransferase status affects mercaptopurine antileukemic effectiveness in a murine model.
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