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Additional information about the drug Sparfloxacin


Sparfloxacin (spar FLOX a sin), trade names Spacin in Bangladesh, Zagam and Zagam Respipac, is a fluoroquinolone antibiotic used in the treatment of bacterial infections. It has a controversial safety profile. Zagam is no longer available in the United States.
Contents
1 Pharmacological properties
2 Medical uses
3 Adverse drug reactions
4 Mechanism of action
5 See also
Suitable quinolones include nalidixic acid, oxolinic acid, cinoxacin, acrosoxacin, pipemedic acid, and the fluoroquinolones flumequine, ciprofloxacin, enoxacin, fleroxacin, grepafloxacin, levofloxacin, lomefloxacin, nadifloxacin, norfloxacin, ofloxacin, pefloxacin, rufloxacin, sparfloxacin, trovafloxacin, danofloxacin, enrofloxacin, and marbofloxacin.

  • Like levofloxacin, sparfloxacin inhibits DNA gyrase preventing replication, repair and recombination in susceptible bacteria. Before the administration of sparfloxacin, culture and sensitivity tests should be done and, sparfloxacin can be administered prior to the results of the culture and sensitivity tests.
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